The prevalence of hyperglycemia among HIV-infected persons who are not receiving antiretroviral therapy is unknown. We conducted a cross-sectional survey to estimate the prevalence of hyperglycemia among Chinese adults with newly diagnosed HIV/AIDS.
Methods: Two thousand and six newly diagnosed HIV/AIDS patients from 10 provinces and municipalities in China were selected during 2009 to 2010.
After an overnight fast, serum samples were collected to measure glucose concentrations. Demographics and medical histories were recorded.
Factors associated with the presence of diabetes were analysed by logistic regression.
Results: Among the 2006 patients, 75.67% were male. Median age was 40 years (range: 18--86 years).
19.99% had hyperglycemia, 9.47% had impaired fasting glucose (IFG) and 10.52% had diabetes. The prevalences of hyperglycemia, of IFG and of diabetes were 21.54%, 10.28% and 11.27% among men and 15.16%, 6.97% and 8.20% among women, respectively.
The prevalence of diabetes increased with increasing age (7.00%, 13.36% and 21.21% among patients who were 18--40, 40--60, and >=60 years of age respectively) and with decreasing CD4 count (6.74%, 8.45%, 9.69%, and 12.66% among patients with CD4 count of >=350, 200--350, 50--200, and <50/mm3 respectively). The prevalence of diabetes was higher among ethnic minority patients than among the Han patients (14.37% versus 9.24%).
The logistic analysis showed that older age, lower CD4 count and minority ethnicity were significantly associated with an increased risk of diabetes.
Conclusions: Hyperglycemia is highly prevalent among Chinese adults with newly diagnosed HIV/AIDS. Older age, lower CD4 count and minority ethnicity are associated with increased risk of diabetes.
All newly diagnosed HIV/AIDS individuals should be routinely evaluated for hyperglycemia.
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